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Rituximab Selectively Suppresses Specific Islet Antibodies

OBJECTIVE: The TrialNet Study Group evaluated rituximab, a B-cell–depleting monoclonal antibody, for its effect in new-onset patients with type 1A diabetes. Rituximab decreased the loss of C-peptide over the first year of follow-up and markedly depleted B lymphocytes for 6 months after administratio...

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Detalles Bibliográficos
Autores principales:	Yu, Liping, Herold, Kevan, Krause-Steinrauf, Heidi, McGee, Paula L., Bundy, Brian, Pugliese, Alberto, Krischer, Jeff, Eisenbarth, George S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2011
Materias:	Immunology and Transplantation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178300/ https://www.ncbi.nlm.nih.gov/pubmed/21831969 http://dx.doi.org/10.2337/db11-0674

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