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A Mycobacterium leprae Hsp65 Mutant as a Candidate for Mitigating Lupus Aggravation in Mice

Hsp60 is an abundant and highly conserved family of intracellular molecules. Increased levels of this family of proteins have been observed in the extracellular compartment in chronic inflammation. Administration of M. leprae Hsp65 [WT] in [NZBxNZW]F(1) mice accelerates the Systemic Lupus Erythemato...

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Detalles Bibliográficos
Autores principales: Marengo, Eliana B., de Moraes, Luciana V., Melo, Robson L., Balan, Andrea, Fernandes, Beatriz L., Tambourgi, Denise V., Rizzo, Luiz Vicente, Sant'Anna, Osvaldo Augusto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178518/
https://www.ncbi.nlm.nih.gov/pubmed/21961033
http://dx.doi.org/10.1371/journal.pone.0024093