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Transgene Excision Has No Impact on In Vivo Integration of Human iPS Derived Neural Precursors
The derivation of induced human pluripotent stem cells (hiPS) has generated significant enthusiasm particularly for the prospects of cell-based therapy. But there are concerns about the suitability of iPS cells for in vivo applications due in part to the introduction of potentially oncogenic transcr...
Autores principales: | Major, Tamara, Menon, Jayanthi, Auyeung, Gordon, Soldner, Frank, Hockemeyer, Dirk, Jaenisch, Rudolf, Tabar, Viviane |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178523/ https://www.ncbi.nlm.nih.gov/pubmed/21961042 http://dx.doi.org/10.1371/journal.pone.0024687 |
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