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Activity Dependent Protein Degradation Is Critical for the Formation and Stability of Fear Memory in the Amygdala
Protein degradation through the ubiquitin-proteasome system [UPS] plays a critical role in some forms of synaptic plasticity. However, its role in memory formation in the amygdala, a site critical for the formation of fear memories, currently remains unknown. Here we provide the first evidence that...
Autores principales: | Jarome, Timothy J., Werner, Craig T., Kwapis, Janine L., Helmstetter, Fred J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178530/ https://www.ncbi.nlm.nih.gov/pubmed/21961035 http://dx.doi.org/10.1371/journal.pone.0024349 |
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