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Bound Water at Protein-Protein Interfaces: Partners, Roles and Hydrophobic Bubbles as a Conserved Motif
BACKGROUND: There is a great interest in understanding and exploiting protein-protein associations as new routes for treating human disease. However, these associations are difficult to structurally characterize or model although the number of X-ray structures for protein-protein complexes is expand...
Autores principales: | Ahmed, Mostafa H., Spyrakis, Francesca, Cozzini, Pietro, Tripathi, Parijat K., Mozzarelli, Andrea, Scarsdale, J. Neel, Safo, Martin A., Kellogg, Glen E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178540/ https://www.ncbi.nlm.nih.gov/pubmed/21961043 http://dx.doi.org/10.1371/journal.pone.0024712 |
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