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Genetic Heterogeneity of Hepatitis C Virus in Association with Antiviral Therapy Determined by Ultra-Deep Sequencing
BACKGROUND AND AIMS: The hepatitis C virus (HCV) invariably shows wide heterogeneity in infected patients, referred to as a quasispecies population. Massive amounts of genetic information due to the abundance of HCV variants could be an obstacle to evaluate the viral genetic heterogeneity in detail....
Autores principales: | Nasu, Akihiro, Marusawa, Hiroyuki, Ueda, Yoshihide, Nishijima, Norihiro, Takahashi, Ken, Osaki, Yukio, Yamashita, Yukitaka, Inokuma, Tetsuro, Tamada, Takashi, Fujiwara, Takeshi, Sato, Fumiaki, Shimizu, Kazuharu, Chiba, Tsutomu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178558/ https://www.ncbi.nlm.nih.gov/pubmed/21966381 http://dx.doi.org/10.1371/journal.pone.0024907 |
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