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Secretion of Genome-Free Hepatitis B Virus – Single Strand Blocking Model for Virion Morphogenesis of Para-retrovirus
As a para-retrovirus, hepatitis B virus (HBV) is an enveloped virus with a double-stranded (DS) DNA genome that is replicated by reverse transcription of an RNA intermediate, the pregenomic RNA or pgRNA. HBV assembly begins with the formation of an “immature” nucleocapsid (NC) incorporating pgRNA, w...
Autores principales: | Ning, Xiaojun, Nguyen, David, Mentzer, Laura, Adams, Christina, Lee, Hyunwook, Ashley, Robert, Hafenstein, Susan, Hu, Jianming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178560/ https://www.ncbi.nlm.nih.gov/pubmed/21966269 http://dx.doi.org/10.1371/journal.ppat.1002255 |
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