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Secretion of Genome-Free Hepatitis B Virus – Single Strand Blocking Model for Virion Morphogenesis of Para-retrovirus

As a para-retrovirus, hepatitis B virus (HBV) is an enveloped virus with a double-stranded (DS) DNA genome that is replicated by reverse transcription of an RNA intermediate, the pregenomic RNA or pgRNA. HBV assembly begins with the formation of an “immature” nucleocapsid (NC) incorporating pgRNA, w...

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Detalles Bibliográficos
Autores principales: Ning, Xiaojun, Nguyen, David, Mentzer, Laura, Adams, Christina, Lee, Hyunwook, Ashley, Robert, Hafenstein, Susan, Hu, Jianming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178560/
https://www.ncbi.nlm.nih.gov/pubmed/21966269
http://dx.doi.org/10.1371/journal.ppat.1002255

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