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Robust Antigen Specific Th17 T Cell Response to Group A Streptococcus Is Dependent on IL-6 and Intranasal Route of Infection
Group A streptococcus (GAS, Streptococcus pyogenes) is the cause of a variety of clinical conditions, ranging from pharyngitis to autoimmune disease. Peptide-major histocompatibility complex class II (pMHCII) tetramers have recently emerged as a highly sensitive means to quantify pMHCII-specific CD4...
Autores principales: | Dileepan, Thamotharampillai, Linehan, Jonathan L., Moon, James J., Pepper, Marion, Jenkins, Marc K., Cleary, Patrick P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178561/ https://www.ncbi.nlm.nih.gov/pubmed/21966268 http://dx.doi.org/10.1371/journal.ppat.1002252 |
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