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Genetic Variants of TSLP and Asthma in an Admixed Urban Population
BACKGROUND: Thymic stromal lymphopoietin (TSLP), an IL7-like cytokine produced by bronchial epithelial cells is upregulated in asthma and induces dendritic cell maturation supporting a Th2 response. Environmental pollutants, including tobacco smoke and diesel exhaust particles upregulate TSLP sugges...
Autores principales: | Liu, Mengling, Rogers, Linda, Cheng, Qinyi, Shao, Yongzhao, Fernandez-Beros, Maria Elena, Hirschhorn, Joel N., Lyon, Helen N., Gajdos, Zofia K. Z., Vedantam, Sailaja, Gregersen, Peter, Seldin, Michael F., Bleck, Bertram, Ramasamy, Adaikalavan, Hartikainen, Anna-Liisa, Jarvelin, Marjo-Riitta, Kuokkanen, Mikko, Laitinen, Tarja, Eriksson, Johan, Lehtimäki, Terho, Raitakari, Olli T., Reibman, Joan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178593/ https://www.ncbi.nlm.nih.gov/pubmed/21966427 http://dx.doi.org/10.1371/journal.pone.0025099 |
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