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Novel Interactions between Actin and the Proteasome Revealed by Complex Haploinsufficiency
Saccharomyces cerevisiae has been a powerful model for uncovering the landscape of binary gene interactions through whole-genome screening. Complex heterozygous interactions are potentially important to human genetic disease as loss-of-function alleles are common in human genomes. We have been using...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178594/ https://www.ncbi.nlm.nih.gov/pubmed/21966278 http://dx.doi.org/10.1371/journal.pgen.1002288 |