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Imaging Pulmonary NF-kappaB Activation and Therapeutic Effects of MLN120B and TDZD-8

NF-κB activation is a critical signaling event in the inflammatory response and has been implicated in a number of pathological lung diseases. To enable the assessment of NF-κB activity in the lungs, we transfected a luciferase based NF-κB reporter into the lungs of mice or into Raw264.7 cells in cu...

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Detalles Bibliográficos
Autores principales: Ansaldi, Dan, Hod, Eldad A., Stellari, Fabio, Kim, Jae-Beom, Lim, Ed, Roskey, Mark, Francis, Kevin P., Singh, Rajendra, Zhang, Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178604/
https://www.ncbi.nlm.nih.gov/pubmed/21966423
http://dx.doi.org/10.1371/journal.pone.0025093