Accelerated CCl(4)-Induced Liver Fibrosis in Hjv-/- Mice, Associated with an Oxidative Burst and Precocious Profibrogenic Gene Expression

Hereditary hemochromatosis is commonly associated with liver fibrosis. Likewise, hepatic iron overload secondary to chronic liver diseases aggravates liver injury. To uncover underlying molecular mechanisms, hemochromatotic hemojuvelin knockout (Hjv-/-) mice and wild type (wt) controls were intoxica...

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Detalles Bibliográficos
Autores principales: Sebastiani, Giada, Gkouvatsos, Kostas, Maffettone, Carmen, Busatto, Graziella, Guido, Maria, Pantopoulos, Kostas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178612/
https://www.ncbi.nlm.nih.gov/pubmed/21966437
http://dx.doi.org/10.1371/journal.pone.0025138

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178612/
https://www.ncbi.nlm.nih.gov/pubmed/21966437
http://dx.doi.org/10.1371/journal.pone.0025138

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