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Aging Negatively Affects Estrogens-Mediated Effects on Nitric Oxide Bioavailability by Shifting ERα/ERβ Balance in Female Mice

AIMS: Aging is among the major causes for the lack of cardiovascular protection by estrogen (E2) during postmenopause. Our study aims to determine the mechanisms whereby aging changes E2 effects on nitric oxide (NO) production in a mouse model of accelerated senescence (SAM). METHODS AND RESULTS: Al...

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Detalles Bibliográficos
Autores principales:	Novensà, Laura, Novella, Susana, Medina, Pascual, Segarra, Gloria, Castillo, Nadia, Heras, Magda, Hermenegildo, Carlos, Dantas, Ana Paula
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178641/ https://www.ncbi.nlm.nih.gov/pubmed/21966501 http://dx.doi.org/10.1371/journal.pone.0025335

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