Cargando…

Spatial and nonspatial implicit motor learning in Korsakoff’s amnesia: evidence for selective deficits

Patients with amnesia have deficits in declarative memory but intact memory for motor and perceptual skills, which suggests that explicit memory and implicit memory are distinct. However, the evidence that implicit motor learning is intact in amnesic patients is contradictory. This study investigate...

Descripción completa

Detalles Bibliográficos
Autores principales: Van Tilborg, Ilse A. D. A., Kessels, Roy P. C., Kruijt, Pauline, Wester, Arie J., Hulstijn, Wouter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178790/
https://www.ncbi.nlm.nih.gov/pubmed/21853284
http://dx.doi.org/10.1007/s00221-011-2841-6
_version_ 1782212437798289408
author Van Tilborg, Ilse A. D. A.
Kessels, Roy P. C.
Kruijt, Pauline
Wester, Arie J.
Hulstijn, Wouter
author_facet Van Tilborg, Ilse A. D. A.
Kessels, Roy P. C.
Kruijt, Pauline
Wester, Arie J.
Hulstijn, Wouter
author_sort Van Tilborg, Ilse A. D. A.
collection PubMed
description Patients with amnesia have deficits in declarative memory but intact memory for motor and perceptual skills, which suggests that explicit memory and implicit memory are distinct. However, the evidence that implicit motor learning is intact in amnesic patients is contradictory. This study investigated implicit sequence learning in amnesic patients with Korsakoff’s syndrome (N = 20) and matched controls (N = 14), using the classical Serial Reaction Time Task and a newly developed Pattern Learning Task in which the planning and execution of the responses are more spatially demanding. Results showed that implicit motor learning occurred in both groups of participants; however, on the Pattern Learning Task, the percentage of errors did not increase in the Korsakoff group in the random test phase, which is indicative of less implicit learning. Thus, our findings show that the performance of patients with Korsakoff’s syndrome is compromised on an implicit learning task with a strong spatial response component.
format Online
Article
Text
id pubmed-3178790
institution National Center for Biotechnology Information
language English
publishDate 2011
publisher Springer-Verlag
record_format MEDLINE/PubMed
spelling pubmed-31787902011-09-30 Spatial and nonspatial implicit motor learning in Korsakoff’s amnesia: evidence for selective deficits Van Tilborg, Ilse A. D. A. Kessels, Roy P. C. Kruijt, Pauline Wester, Arie J. Hulstijn, Wouter Exp Brain Res Research Article Patients with amnesia have deficits in declarative memory but intact memory for motor and perceptual skills, which suggests that explicit memory and implicit memory are distinct. However, the evidence that implicit motor learning is intact in amnesic patients is contradictory. This study investigated implicit sequence learning in amnesic patients with Korsakoff’s syndrome (N = 20) and matched controls (N = 14), using the classical Serial Reaction Time Task and a newly developed Pattern Learning Task in which the planning and execution of the responses are more spatially demanding. Results showed that implicit motor learning occurred in both groups of participants; however, on the Pattern Learning Task, the percentage of errors did not increase in the Korsakoff group in the random test phase, which is indicative of less implicit learning. Thus, our findings show that the performance of patients with Korsakoff’s syndrome is compromised on an implicit learning task with a strong spatial response component. Springer-Verlag 2011-08-19 2011 /pmc/articles/PMC3178790/ /pubmed/21853284 http://dx.doi.org/10.1007/s00221-011-2841-6 Text en © The Author(s) 2011 https://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.
spellingShingle Research Article
Van Tilborg, Ilse A. D. A.
Kessels, Roy P. C.
Kruijt, Pauline
Wester, Arie J.
Hulstijn, Wouter
Spatial and nonspatial implicit motor learning in Korsakoff’s amnesia: evidence for selective deficits
title Spatial and nonspatial implicit motor learning in Korsakoff’s amnesia: evidence for selective deficits
title_full Spatial and nonspatial implicit motor learning in Korsakoff’s amnesia: evidence for selective deficits
title_fullStr Spatial and nonspatial implicit motor learning in Korsakoff’s amnesia: evidence for selective deficits
title_full_unstemmed Spatial and nonspatial implicit motor learning in Korsakoff’s amnesia: evidence for selective deficits
title_short Spatial and nonspatial implicit motor learning in Korsakoff’s amnesia: evidence for selective deficits
title_sort spatial and nonspatial implicit motor learning in korsakoff’s amnesia: evidence for selective deficits
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178790/
https://www.ncbi.nlm.nih.gov/pubmed/21853284
http://dx.doi.org/10.1007/s00221-011-2841-6
work_keys_str_mv AT vantilborgilseada spatialandnonspatialimplicitmotorlearninginkorsakoffsamnesiaevidenceforselectivedeficits
AT kesselsroypc spatialandnonspatialimplicitmotorlearninginkorsakoffsamnesiaevidenceforselectivedeficits
AT kruijtpauline spatialandnonspatialimplicitmotorlearninginkorsakoffsamnesiaevidenceforselectivedeficits
AT westerariej spatialandnonspatialimplicitmotorlearninginkorsakoffsamnesiaevidenceforselectivedeficits
AT hulstijnwouter spatialandnonspatialimplicitmotorlearninginkorsakoffsamnesiaevidenceforselectivedeficits