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Development and characterization of nanosuspensions of olmesartan medoxomil for bioavailability enhancement
BACKGROUND: Olmesartan medoxomil (OLM), an anti-hypertensive agent administered orally has absolute bioavailability of only 26% due to the poor aqueous solubility (<7.75 μg/ml). The present investigation aimed at enhancing the oral bioavailability of OLM by improving its solubility and dissolutio...
Autores principales: | Thakkar, Hetal Paresh, Patel, Bindesh Vishnubhai, Thakkar, Sneha Piyush |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications Pvt Ltd
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178951/ https://www.ncbi.nlm.nih.gov/pubmed/21966165 http://dx.doi.org/10.4103/0975-7406.84459 |
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