Cargando…

Polymers for Colon Targeted Drug Delivery

The colon targeted drug delivery has a number of important implications in the field of pharmacotherapy. Oral colon targeted drug delivery systems have recently gained importance for delivering a variety of therapeutic agents for both local and systemic administration. Targeting of drugs to the colo...

Descripción completa

Detalles Bibliográficos
Autores principales: Rajpurohit, H., Sharma, P., Sharma, S., Bhandari, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178968/
https://www.ncbi.nlm.nih.gov/pubmed/21969739
http://dx.doi.org/10.4103/0250-474X.84576
_version_ 1782212468810973184
author Rajpurohit, H.
Sharma, P.
Sharma, S.
Bhandari, A.
author_facet Rajpurohit, H.
Sharma, P.
Sharma, S.
Bhandari, A.
author_sort Rajpurohit, H.
collection PubMed
description The colon targeted drug delivery has a number of important implications in the field of pharmacotherapy. Oral colon targeted drug delivery systems have recently gained importance for delivering a variety of therapeutic agents for both local and systemic administration. Targeting of drugs to the colon via oral administration protect the drug from degradation or release in the stomach and small intestine. It also ensures abrupt or controlled release of the drug in the proximal colon. Various drug delivery systems have been designed that deliver the drug quantitatively to the colon and then trigger the release of drug. This review will cover different types of polymers which can be used in formulation of colon targeted drug delivery systems.
format Online
Article
Text
id pubmed-3178968
institution National Center for Biotechnology Information
language English
publishDate 2010
publisher Medknow Publications
record_format MEDLINE/PubMed
spelling pubmed-31789682011-10-03 Polymers for Colon Targeted Drug Delivery Rajpurohit, H. Sharma, P. Sharma, S. Bhandari, A. Indian J Pharm Sci Review Article The colon targeted drug delivery has a number of important implications in the field of pharmacotherapy. Oral colon targeted drug delivery systems have recently gained importance for delivering a variety of therapeutic agents for both local and systemic administration. Targeting of drugs to the colon via oral administration protect the drug from degradation or release in the stomach and small intestine. It also ensures abrupt or controlled release of the drug in the proximal colon. Various drug delivery systems have been designed that deliver the drug quantitatively to the colon and then trigger the release of drug. This review will cover different types of polymers which can be used in formulation of colon targeted drug delivery systems. Medknow Publications 2010 /pmc/articles/PMC3178968/ /pubmed/21969739 http://dx.doi.org/10.4103/0250-474X.84576 Text en Copyright: © Indian Journal of Pharmaceutical Sciences http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Rajpurohit, H.
Sharma, P.
Sharma, S.
Bhandari, A.
Polymers for Colon Targeted Drug Delivery
title Polymers for Colon Targeted Drug Delivery
title_full Polymers for Colon Targeted Drug Delivery
title_fullStr Polymers for Colon Targeted Drug Delivery
title_full_unstemmed Polymers for Colon Targeted Drug Delivery
title_short Polymers for Colon Targeted Drug Delivery
title_sort polymers for colon targeted drug delivery
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178968/
https://www.ncbi.nlm.nih.gov/pubmed/21969739
http://dx.doi.org/10.4103/0250-474X.84576
work_keys_str_mv AT rajpurohith polymersforcolontargeteddrugdelivery
AT sharmap polymersforcolontargeteddrugdelivery
AT sharmas polymersforcolontargeteddrugdelivery
AT bhandaria polymersforcolontargeteddrugdelivery