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Polymers for Colon Targeted Drug Delivery
The colon targeted drug delivery has a number of important implications in the field of pharmacotherapy. Oral colon targeted drug delivery systems have recently gained importance for delivering a variety of therapeutic agents for both local and systemic administration. Targeting of drugs to the colo...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178968/ https://www.ncbi.nlm.nih.gov/pubmed/21969739 http://dx.doi.org/10.4103/0250-474X.84576 |
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author | Rajpurohit, H. Sharma, P. Sharma, S. Bhandari, A. |
author_facet | Rajpurohit, H. Sharma, P. Sharma, S. Bhandari, A. |
author_sort | Rajpurohit, H. |
collection | PubMed |
description | The colon targeted drug delivery has a number of important implications in the field of pharmacotherapy. Oral colon targeted drug delivery systems have recently gained importance for delivering a variety of therapeutic agents for both local and systemic administration. Targeting of drugs to the colon via oral administration protect the drug from degradation or release in the stomach and small intestine. It also ensures abrupt or controlled release of the drug in the proximal colon. Various drug delivery systems have been designed that deliver the drug quantitatively to the colon and then trigger the release of drug. This review will cover different types of polymers which can be used in formulation of colon targeted drug delivery systems. |
format | Online Article Text |
id | pubmed-3178968 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2010 |
publisher | Medknow Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-31789682011-10-03 Polymers for Colon Targeted Drug Delivery Rajpurohit, H. Sharma, P. Sharma, S. Bhandari, A. Indian J Pharm Sci Review Article The colon targeted drug delivery has a number of important implications in the field of pharmacotherapy. Oral colon targeted drug delivery systems have recently gained importance for delivering a variety of therapeutic agents for both local and systemic administration. Targeting of drugs to the colon via oral administration protect the drug from degradation or release in the stomach and small intestine. It also ensures abrupt or controlled release of the drug in the proximal colon. Various drug delivery systems have been designed that deliver the drug quantitatively to the colon and then trigger the release of drug. This review will cover different types of polymers which can be used in formulation of colon targeted drug delivery systems. Medknow Publications 2010 /pmc/articles/PMC3178968/ /pubmed/21969739 http://dx.doi.org/10.4103/0250-474X.84576 Text en Copyright: © Indian Journal of Pharmaceutical Sciences http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Rajpurohit, H. Sharma, P. Sharma, S. Bhandari, A. Polymers for Colon Targeted Drug Delivery |
title | Polymers for Colon Targeted Drug Delivery |
title_full | Polymers for Colon Targeted Drug Delivery |
title_fullStr | Polymers for Colon Targeted Drug Delivery |
title_full_unstemmed | Polymers for Colon Targeted Drug Delivery |
title_short | Polymers for Colon Targeted Drug Delivery |
title_sort | polymers for colon targeted drug delivery |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178968/ https://www.ncbi.nlm.nih.gov/pubmed/21969739 http://dx.doi.org/10.4103/0250-474X.84576 |
work_keys_str_mv | AT rajpurohith polymersforcolontargeteddrugdelivery AT sharmap polymersforcolontargeteddrugdelivery AT sharmas polymersforcolontargeteddrugdelivery AT bhandaria polymersforcolontargeteddrugdelivery |