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A New Benzofuran Glucoside from Ficus Tikoua Bur

From the water-soluble portion of the methanol extract of stems of Ficus tikoua Bur., a new benzofuran glucoside, named 6-carboxyethyl-5-hydroxybenzofuran 5-O-β-d-glucopyranoside (1), together with one known benzofuran glucoside (2) were isolated. Their structures were elucidated by 1D and 2D ((1)H-...

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Detalles Bibliográficos
Autores principales: Wei, Shao-Peng, Luan, Jie-Yu, Lu, Li-Na, Wu, Wen-Jun, Ji, Zhi-Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179143/
https://www.ncbi.nlm.nih.gov/pubmed/21954336
http://dx.doi.org/10.3390/ijms12084946
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author Wei, Shao-Peng
Luan, Jie-Yu
Lu, Li-Na
Wu, Wen-Jun
Ji, Zhi-Qin
author_facet Wei, Shao-Peng
Luan, Jie-Yu
Lu, Li-Na
Wu, Wen-Jun
Ji, Zhi-Qin
author_sort Wei, Shao-Peng
collection PubMed
description From the water-soluble portion of the methanol extract of stems of Ficus tikoua Bur., a new benzofuran glucoside, named 6-carboxyethyl-5-hydroxybenzofuran 5-O-β-d-glucopyranoside (1), together with one known benzofuran glucoside (2) were isolated. Their structures were elucidated by 1D and 2D ((1)H-(1)H COSY, HMQC, and HMBC) NMR spectroscopy and HRMS techniques. The antioxidant activities of the isolated compounds were assayed based on the scavenging activities of DPPH free radical. Compounds 1 and 2 exhibited moderate antioxidant activities, and the IC(50) values were 242.8 μg·mL(−1) and 324.9 μg·mL(−1), respectively.
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spelling pubmed-31791432011-09-27 A New Benzofuran Glucoside from Ficus Tikoua Bur Wei, Shao-Peng Luan, Jie-Yu Lu, Li-Na Wu, Wen-Jun Ji, Zhi-Qin Int J Mol Sci Article From the water-soluble portion of the methanol extract of stems of Ficus tikoua Bur., a new benzofuran glucoside, named 6-carboxyethyl-5-hydroxybenzofuran 5-O-β-d-glucopyranoside (1), together with one known benzofuran glucoside (2) were isolated. Their structures were elucidated by 1D and 2D ((1)H-(1)H COSY, HMQC, and HMBC) NMR spectroscopy and HRMS techniques. The antioxidant activities of the isolated compounds were assayed based on the scavenging activities of DPPH free radical. Compounds 1 and 2 exhibited moderate antioxidant activities, and the IC(50) values were 242.8 μg·mL(−1) and 324.9 μg·mL(−1), respectively. Molecular Diversity Preservation International (MDPI) 2011-08-03 /pmc/articles/PMC3179143/ /pubmed/21954336 http://dx.doi.org/10.3390/ijms12084946 Text en © 2011 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0 This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Wei, Shao-Peng
Luan, Jie-Yu
Lu, Li-Na
Wu, Wen-Jun
Ji, Zhi-Qin
A New Benzofuran Glucoside from Ficus Tikoua Bur
title A New Benzofuran Glucoside from Ficus Tikoua Bur
title_full A New Benzofuran Glucoside from Ficus Tikoua Bur
title_fullStr A New Benzofuran Glucoside from Ficus Tikoua Bur
title_full_unstemmed A New Benzofuran Glucoside from Ficus Tikoua Bur
title_short A New Benzofuran Glucoside from Ficus Tikoua Bur
title_sort new benzofuran glucoside from ficus tikoua bur
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179143/
https://www.ncbi.nlm.nih.gov/pubmed/21954336
http://dx.doi.org/10.3390/ijms12084946
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