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Inhibitory Effects of Megakaryocytic Cells in Prostate Cancer Skeletal Metastasis
Prostate cancer cells commonly spread through the circulation, but few successfully generate metastatic foci in bone. Osteoclastic cellular activity has been proposed as an initiating event for skeletal metastasis. Megakaryocytes (MKs) inhibit osteoclastogenesis, which could have an impact on tumor...
Autores principales: | Li, Xin, Koh, Amy J, Wang, Zhengyan, Soki, Fabiana N, Park, Serk In, Pienta, Kenneth J, McCauley, Laurie K |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wiley Subscription Services, Inc., A Wiley Company
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179321/ https://www.ncbi.nlm.nih.gov/pubmed/20684002 http://dx.doi.org/10.1002/jbmr.204 |
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