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Inhibitory Effects of Megakaryocytic Cells in Prostate Cancer Skeletal Metastasis

Prostate cancer cells commonly spread through the circulation, but few successfully generate metastatic foci in bone. Osteoclastic cellular activity has been proposed as an initiating event for skeletal metastasis. Megakaryocytes (MKs) inhibit osteoclastogenesis, which could have an impact on tumor...

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Detalles Bibliográficos
Autores principales: Li, Xin, Koh, Amy J, Wang, Zhengyan, Soki, Fabiana N, Park, Serk In, Pienta, Kenneth J, McCauley, Laurie K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179321/
https://www.ncbi.nlm.nih.gov/pubmed/20684002
http://dx.doi.org/10.1002/jbmr.204

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