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Nell-1, a key Functional Mediator of Runx2, Partially Rescues Calvarial Defects in Runx2(+/−) Mice
Mesenchymal stem cell commitment to an osteoprogenitor lineage requires the activity of Runx2, a molecule implicated in the etiopathology of multiple congenital craniofacial anomalies. Through promoter analyses, we have recently identified a new direct transcriptional target of Runx2, Nell-1, a cran...
Autores principales: | Zhang, Xinli, Ting, Kang, Bessette, Catherine M, Culiat, Cymbeline T, Sung, Sang Jin, Lee, Haofu, Chen, Feng, Shen, Jia, Wang, James J, Kuroda, Shun'ichi, Soo, Chia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wiley Subscription Services, Inc., A Wiley Company
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179324/ https://www.ncbi.nlm.nih.gov/pubmed/20939017 http://dx.doi.org/10.1002/jbmr.267 |
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