Cargando…

Multi-ethnic studies in complex traits

The successes of genome-wide association (GWA) studies have mainly come from studies performed in populations of European descent. Since complex traits are characterized by marked genetic heterogeneity, the findings so far may provide an incomplete picture of the genetic architecture of complex trai...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fu, Jingyuan, Festen, Eleonora A.M., Wijmenga, Cisca
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2011
Materias:	Reviews
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179384/ https://www.ncbi.nlm.nih.gov/pubmed/21890495 http://dx.doi.org/10.1093/hmg/ddr386

Ejemplares similares

Studying the gut virome in the metagenomic era: challenges and perspectives
por: Garmaeva, Sanzhima, et al.
Publicado: (2019)

Anti-inflammatory Gut Microbial Pathways Are Decreased During Crohn’s Disease Exacerbations
por: Klaassen, Marjolein A Y, et al.
Publicado: (2019)

SLC39A8 missense variant is associated with Crohn's disease but does not have a major impact on gut microbiome composition in healthy subjects
por: Collij, Valerie, et al.
Publicado: (2019)

From genome-wide association studies to disease mechanisms: celiac disease as a model for autoimmune diseases
por: Kumar, Vinod, et al.
Publicado: (2012)

Context-specific effects of genetic variants associated with autoimmune disease
por: Jonkers, Iris H., et al.
Publicado: (2017)

Expressing the Differences between Crohn Disease and Ulcerative Colitis
por: Wijmenga, Cisca
Publicado: (2005)

Pharmacomicrobiomics: a novel route towards personalized medicine?
por: Doestzada, Marwah, et al.
Publicado: (2018)

The MHC locus and genetic susceptibility to autoimmune and infectious diseases
por: Matzaraki, Vasiliki, et al.
Publicado: (2017)

Celiac disease-on-chip: Modeling a multifactorial disease in vitro
por: Moerkens, Renée, et al.
Publicado: (2019)

Long Non-Coding RNAs Involved in Progression of Non-Alcoholic Fatty Liver Disease to Steatohepatitis
por: Atanasovska, Biljana, et al.
Publicado: (2021)

Eosinophil Count Is a Common Factor for Complex Metabolic and Pulmonary Traits and Diseases: The LifeLines Cohort Study
por: Amini, Marzyeh, et al.
Publicado: (2016)

The Impact of Donor and Recipient Genetic Variation on Outcomes After Solid Organ Transplantation: A Scoping Review and Future Perspectives
por: Li, Yanni, et al.
Publicado: (2021)

Health behaviors and metabolic risk factors are associated with dyslipidemia in ethnic Miao Chinese adults: the China multi-ethnic cohort study
por: Nie, Fang, et al.
Publicado: (2021)

Whole exome sequencing analyses reveal gene–microbiota interactions in the context of IBD
por: Hu, Shixian, et al.
Publicado: (2021)

Role of the gut microbiome in mediating lactose intolerance symptoms
por: Brandao Gois, M F, et al.
Publicado: (2022)

No Evidence in a Large UK Collection for Celiac Disease Risk Variants Reported by a Spanish Study
por: Hunt, Karen A., et al.
Publicado: (2008)

Detection of stable community structures within gut microbiota co-occurrence networks from different human populations
por: Jackson, Matthew A., et al.
Publicado: (2018)

Omics-informed CNV calls reduce false-positive rates and improve power for CNV-trait associations
por: Lepamets, Maarja, et al.
Publicado: (2022)

Relationship between gut microbiota and circulating metabolites in population-based cohorts
por: Vojinovic, Dina, et al.
Publicado: (2019)

Lack of Association Between Genetic Variants at ACE2 and TMPRSS2 Genes Involved in SARS-CoV-2 Infection and Human Quantitative Phenotypes
por: Lopera Maya, Esteban A., et al.
Publicado: (2020)

A GWAS meta-analysis suggests roles for xenobiotic metabolism and ion channel activity in the biology of stool frequency
por: Jankipersadsing, Soesma A, et al.
Publicado: (2017)

Impact of occupational pesticide exposure on the human gut microbiome
por: Gois, Milla F. Brandao, et al.
Publicado: (2023)

Complex nature of SNP genotype effects on gene expression in primary human leucocytes
por: Heap, Graham A, et al.
Publicado: (2009)

Ethnic variation of selected dental traits in Coorg
por: Uthaman, Chancy, et al.
Publicado: (2015)

Explaining racial/ethnic differences in all-cause mortality in the Multi-Ethnic Study of Atherosclerosis (MESA): Substantive complexity and hazardous working conditions as mediating factors
por: Fujishiro, Kaori, et al.
Publicado: (2017)

Perceived ethnic discrimination, suicidal ideation and mastery in a multi-ethnic cohort: the HELIUS study
por: Willemen, Fabienne E. M., et al.
Publicado: (2023)

Ethnic, Geographic and Dietary Differences in Arsenic Exposure in the Multi-Ethnic Study of Atherosclerosis (MESA)
por: Jones, Miranda R., et al.
Publicado: (2018)

Genetic associations with lipoprotein subfraction measures differ by ethnicity in the multi-ethnic study of atherosclerosis (MESA)
por: Wang, Zhe, et al.
Publicado: (2017)

Functional Annotation of Genetic Loci Associated With Sepsis Prioritizes Immune and Endothelial Cell Pathways
por: Le, Kieu T. T., et al.
Publicado: (2019)

Cardiovascular magnetic resonance in an adult human population: serial observations from the multi-ethnic study of atherosclerosis
por: Yoneyama, Kihei, et al.
Publicado: (2017)

Adolescents in Multi-Ethnic Families under Korean Ethnic Nationalism
por: Cho, Hae-Wol, et al.
Publicado: (2017)

Patient attitudes towards faecal sampling for gut microbiome studies and clinical care reveal positive engagement and room for improvement
por: Bolte, Laura A., et al.
Publicado: (2021)

MultiBLUP: improved SNP-based prediction for complex traits
por: Speed, Doug, et al.
Publicado: (2014)

Identifying Multi-Omics Causers and Causal Pathways for Complex Traits
por: Qin, Huaizhen, et al.
Publicado: (2019)

The Gut Microbiome Contributes to a Substantial Proportion of the Variation in Blood Lipids
por: Fu, Jingyuan, et al.
Publicado: (2015)

Comparing self-reported ethnicity to genetic background measures in the context of the Multi-Ethnic Study of Atherosclerosis (MESA)
por: Divers, Jasmin, et al.
Publicado: (2011)

Long-term dietary patterns are associated with pro-inflammatory and anti-inflammatory features of the gut microbiome
por: Bolte, Laura A, et al.
Publicado: (2021)

Genomic characterization of the RH locus detects complex and novel structural variation in multi-ethnic cohorts
por: Wheeler, Marsha M., et al.
Publicado: (2018)

Multi-ethnic genome-wide association analyses of white blood cell and platelet traits in the Population Architecture using Genomics and Epidemiology (PAGE) study
por: Hu, Yao, et al.
Publicado: (2021)

A Meta-Analysis of Genome-Wide Association Scans Identifies IL18RAP, PTPN2, TAGAP, and PUS10 As Shared Risk Loci for Crohn's Disease and Celiac Disease
por: Festen, Eleonora A. M., et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_u06h76rcf3en60verlpkg78t78