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Progressive severe lung injury by zinc oxide nanoparticles; the role of Zn(2+ )dissolution inside lysosomes

BACKGROUND: Large production volumes of zinc oxide nanoparticles (ZnONP) might be anticipated to pose risks, of accidental inhalation in occupational and even in consumer settings. Herein, we further investigated the pathological changes induced by ZnONP and their possible mechanism of action. METHO...

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Detalles Bibliográficos
Autores principales:	Cho, Wan-Seob, Duffin, Rodger, Howie, Sarah EM, Scotton, Chris J, Wallace, William AH, MacNee, William, Bradley, Mark, Megson, Ian L, Donaldson, Ken
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179432/ https://www.ncbi.nlm.nih.gov/pubmed/21896169 http://dx.doi.org/10.1186/1743-8977-8-27

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