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Temporal Regulation of Rapamycin on Memory CTL Programming by IL-12

Mammalian target of rapamycin (mTOR) is a master regulator of cell growth. Recent reports have defined its important role in memory cytotoxic T lymphocyte (CTL) differentiation in infections and memory programming. We report that rapamycin regulated memory CTL programming by IL-12 to a similar level...

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Detalles Bibliográficos
Autores principales: Li, Xiangdong, Garcia, Karla, Sun, Zhifeng, Xiao, Zhengguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179471/
https://www.ncbi.nlm.nih.gov/pubmed/21966447
http://dx.doi.org/10.1371/journal.pone.0025177