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Imaging of Zebrafish In Vivo with Second-Harmonic Generation Reveals Shortened Sarcomeres Associated with Myopathy Induced by Statin
We employed second-harmonic generation (SHG) imaging and the zebrafish model to investigate the myopathy caused by statin in vivo with emphasis on the altered microstructures of the muscle sarcomere, the fundamental contractile element of muscles. This approach derives an advantage of SHG imaging to...
Autores principales: | Huang, Shih-Hao, Hsiao, Chung-Der, Lin, Dar-Shong, Chow, Cho-Yen, Chang, Chia-Jen, Liau, Ian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179478/ https://www.ncbi.nlm.nih.gov/pubmed/21966365 http://dx.doi.org/10.1371/journal.pone.0024764 |
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