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Imaging of Zebrafish In Vivo with Second-Harmonic Generation Reveals Shortened Sarcomeres Associated with Myopathy Induced by Statin

We employed second-harmonic generation (SHG) imaging and the zebrafish model to investigate the myopathy caused by statin in vivo with emphasis on the altered microstructures of the muscle sarcomere, the fundamental contractile element of muscles. This approach derives an advantage of SHG imaging to...

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Detalles Bibliográficos
Autores principales: Huang, Shih-Hao, Hsiao, Chung-Der, Lin, Dar-Shong, Chow, Cho-Yen, Chang, Chia-Jen, Liau, Ian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179478/
https://www.ncbi.nlm.nih.gov/pubmed/21966365
http://dx.doi.org/10.1371/journal.pone.0024764

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