Cargando…
CYP5122A1, a Novel Cytochrome P450 Is Essential for Survival of Leishmania donovani
BACKGROUND: Cytochrome P450s (CYP450s) are hemoproteins catalysing diverse biochemical reactions important for metabolism of xenobiotics and synthesis of physiologically important compounds such as sterols. Therefore, they are functionally important for survival of invading pathogens. One such oppor...
Autores principales: | Verma, Smriti, Mehta, Ashish, Shaha, Chandrima |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179497/ https://www.ncbi.nlm.nih.gov/pubmed/21966477 http://dx.doi.org/10.1371/journal.pone.0025273 |
Ejemplares similares
-
CYP5122A1 encodes an essential sterol C4-methyl oxidase in Leishmania donovani and determines the antileishmanial activity of antifungal azoles
por: Jin, Yiru, et al.
Publicado: (2023) -
Leishmania donovani-Induced Increase in Macrophage Bcl-2 Favors Parasite Survival
por: Pandey, Rajeev Kumar, et al.
Publicado: (2016) -
Leishmania donovani parasite requires Atg8 protein for infectivity and survival under stress
por: Giri, Sagnik, et al.
Publicado: (2019) -
Tissue/Biofluid Specific Molecular Cartography of Leishmania donovani Infected BALB/c Mice: Deciphering Systemic Reprogramming
por: Das, Sanchita, et al.
Publicado: (2021) -
Zinc depletion promotes apoptosis-like death in drug-sensitive and antimony-resistance Leishmania donovani
por: Saini, Shalini, et al.
Publicado: (2017)