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Synthesis and Evaluation of (99m)Tc-Labelled Monoclonal Antibody 1D09C3 for Molecular Imaging of Major Histocompatibility Complex Class II Protein Expression

PURPOSE: It is known that major histocompatibility complex class II protein HLA-DR is highly expressed in B-cell lymphomas and in a variety of autoimmune and inflammatory diseases. Therefore, a radiolabelled fully humanized IgG4 monoclonal antibody (mAb) can provide useful prognostic and diagnostic...

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Detalles Bibliográficos
Autores principales:	Malviya, Gaurav, de Vries, E. F. J., Dierckx, Rudi A., Signore, Alberto
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer-Verlag 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179591/ https://www.ncbi.nlm.nih.gov/pubmed/20812032 http://dx.doi.org/10.1007/s11307-010-0407-9

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