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A whole blood monokine-based reporter assay provides a sensitive and robust measurement of the antigen-specific T cell response
BACKGROUND: The ability to measure T-cell responses to antigens is proving critical in the field of vaccine development and for understanding immunity to pathogens, allergens and self-antigens. Although a variety of technologies exist for this purpose IFNγ-ELISpot assays are widely used because of t...
Autores principales: | Chakera, Aron, Bennett, Sophia C, Cornall, Richard J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179727/ https://www.ncbi.nlm.nih.gov/pubmed/21871084 http://dx.doi.org/10.1186/1479-5876-9-143 |
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