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Lifestyle Change Influences on GERD in Japan: A Study of Participants in a Health Examination Program

BACKGROUND: Though gastroesophageal reflux disease (GERD) has been a prevalent disease in Western countries, the incidence of GERD has only just started to increase in Japan. AIM: The aim of this study was to determine which lifestyle factors may be associated with GERD in Japan. METHODS: A total of...

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Detalles Bibliográficos
Autores principales: Murao, Tetsuya, Sakurai, Kouichi, Mihara, Syuuichi, Marubayashi, Toru, Murakami, Yoshitaka, Sasaki, Yutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179841/
https://www.ncbi.nlm.nih.gov/pubmed/21487772
http://dx.doi.org/10.1007/s10620-011-1679-x
Descripción
Sumario:BACKGROUND: Though gastroesophageal reflux disease (GERD) has been a prevalent disease in Western countries, the incidence of GERD has only just started to increase in Japan. AIM: The aim of this study was to determine which lifestyle factors may be associated with GERD in Japan. METHODS: A total of 2,853 participants who took part in a health examination program between July 2004 and March 2005 were enrolled. GERD symptoms were assessed using the Japanese version of the Carlsson-Dent self-administered questionnaire (QUEST). The GERD group consisted of participants with a QUEST score ≥6 and/or endoscopic findings. The GERD group was divided into asymptomatic ERD (erosive reflux disease with no symptoms), symptomatic ERD (erosive reflux disease with symptoms) and NERD (non-erosive reflux disease) groups. Associated factors for these diseases were analyzed by logistic regression analysis. RESULTS: GERD was diagnosed in 667 (23.4%) participants. Among the subjects placed in the GERD group, asymptomatic ERD, symptomatic ERD and NERD were diagnosed in 232 (8.1%), 91 (3.2%) and 344 (12.1%) participants, respectively. Factors associated with GERD included a high BMI (body mass index), hiatus hernia, fewer hours of sleep, lack of exercise, and drinking green tea. CONCLUSIONS: Relationships between lifestyle, gender and GERD were investigated in the present study. Both lifestyle improvements and consideration of gender differences can be used to help prevent GERD development.