Desipramine treatment has minimal effects on the brain accumulation of glucocorticoids in P-gp-deficient and wild-type mice

Hyperactivity of the hypothalamic-pituitary-adrenal (HPA) axis in patients with depression can be reduced by antidepressants, which are thought to improve endogenous glucocorticoid-mediated negative feedback. A proportion of peripherally released glucocorticoids need to enter brain tissue, protected...

Descripción completa

Detalles Bibliográficos
Autores principales: Mason, Brittany L., Thomas, Sarah A., Lightman, Stafford L., Pariante, Carmine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pergamon Press 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179986/
https://www.ncbi.nlm.nih.gov/pubmed/21481537
http://dx.doi.org/10.1016/j.psyneuen.2011.03.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179986/
https://www.ncbi.nlm.nih.gov/pubmed/21481537
http://dx.doi.org/10.1016/j.psyneuen.2011.03.008

Ejemplares similares