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Immunity and AAV-Mediated Gene Therapy for Muscular Dystrophies in Large Animal Models and Human Trials

Adeno-associated viral (AAV) vector-mediated gene replacement for the treatment of muscular dystrophy represents a promising therapeutic strategy in modern medicine. One major obstacle in using AAV vectors for in vivo gene delivery is the development of host immune responses to the viral capsid prot...

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Detalles Bibliográficos
Autores principales: Wang, Zejing, Tapscott, Stephen J., Chamberlain, Jeffrey S., Storb, Rainer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3180173/
https://www.ncbi.nlm.nih.gov/pubmed/21980317
http://dx.doi.org/10.3389/fmicb.2011.00201

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