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Does Compound I Vary Significantly between Isoforms of Cytochrome P450?
[Image: see text] The cytochrome P450 (CYP) enzymes are important in many areas, including pharmaceutical development. Subtle changes in the electronic structure of the active species, Compound I, have been postulated previously to account partly for the experimentally observed differences in reacti...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3180200/ https://www.ncbi.nlm.nih.gov/pubmed/21863858 http://dx.doi.org/10.1021/ja203157u |