Transcriptional responses of the nerve agent-sensitive brain regions amygdala, hippocampus, piriform cortex, septum, and thalamus following exposure to the organophosphonate anticholinesterase sarin

BACKGROUND: Although the acute toxicity of organophosphorus nerve agents is known to result from acetylcholinesterase inhibition, the molecular mechanisms involved in the development of neuropathology following nerve agent-induced seizure are not well understood. To help determine these pathways, we...

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Detalles Bibliográficos
Autores principales: Spradling, Kimberly D, Lumley, Lucille A, Robison, Christopher L, Meyerhoff, James L, Dillman, James F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3180277/
https://www.ncbi.nlm.nih.gov/pubmed/21777430
http://dx.doi.org/10.1186/1742-2094-8-84

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3180277/
https://www.ncbi.nlm.nih.gov/pubmed/21777430
http://dx.doi.org/10.1186/1742-2094-8-84

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