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Transcriptional responses of the nerve agent-sensitive brain regions amygdala, hippocampus, piriform cortex, septum, and thalamus following exposure to the organophosphonate anticholinesterase sarin
BACKGROUND: Although the acute toxicity of organophosphorus nerve agents is known to result from acetylcholinesterase inhibition, the molecular mechanisms involved in the development of neuropathology following nerve agent-induced seizure are not well understood. To help determine these pathways, we...
Autores principales: | Spradling, Kimberly D, Lumley, Lucille A, Robison, Christopher L, Meyerhoff, James L, Dillman, James F |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3180277/ https://www.ncbi.nlm.nih.gov/pubmed/21777430 http://dx.doi.org/10.1186/1742-2094-8-84 |
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