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Fine-Tuning Roles of Endogenous Brain-Derived Neurotrophic Factor, TrkB and Sortilin in Colorectal Cancer Cell Survival

BACKGROUND: Neurotrophin receptors were initially identified in neural cells. They were recently detected in some cancers in association with invasiveness, but the function of these tyrosine kinase receptors was not previously investigated in colorectal cancer (CRC) cells. METHODS AND FINDINGS: We r...

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Detalles Bibliográficos
Autores principales: Akil, Hussein, Perraud, Aurélie, Mélin, Carole, Jauberteau, Marie-Odile, Mathonnet, Muriel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3180371/
https://www.ncbi.nlm.nih.gov/pubmed/21966426
http://dx.doi.org/10.1371/journal.pone.0025097