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IsoformEx: isoform level gene expression estimation using weighted non-negative least squares from mRNA-Seq data
BACKGROUND: mRNA-Seq technology has revolutionized the field of transcriptomics for identification and quantification of gene transcripts not only at gene level but also at isoform level. Estimating the expression levels of transcript isoforms from mRNA-Seq data is a challenging problem due to the p...
Autores principales: | Kim, Hyunsoo, Bi, Yingtao, Pal, Sharmistha, Gupta, Ravi, Davuluri, Ramana V |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3180389/ https://www.ncbi.nlm.nih.gov/pubmed/21794104 http://dx.doi.org/10.1186/1471-2105-12-305 |
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