Cargando…

Malignant peritoneal mesothelioma presenting as recurrent adhesion obstruction in general surgery: a case report

INTRODUCTION: Malignant peritoneal mesothelioma is a well-described entity in many reports in the literature in which it has been associated with asbestosis. However, there is no information describing the gross appearance and cardinal features seen during laparotomy, hence it is easy for the unwary...

Descripción completa

Detalles Bibliográficos
Autores principales: Naraynsingh, Vijay, Ramdass, Michael J, Lum, Crystal Lee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3180415/
https://www.ncbi.nlm.nih.gov/pubmed/21878098
http://dx.doi.org/10.1186/1752-1947-5-420
_version_ 1782212631567794176
author Naraynsingh, Vijay
Ramdass, Michael J
Lum, Crystal Lee
author_facet Naraynsingh, Vijay
Ramdass, Michael J
Lum, Crystal Lee
author_sort Naraynsingh, Vijay
collection PubMed
description INTRODUCTION: Malignant peritoneal mesothelioma is a well-described entity in many reports in the literature in which it has been associated with asbestosis. However, there is no information describing the gross appearance and cardinal features seen during laparotomy, hence it is easy for the unwary surgeon to miss the diagnosis of this rare condition. CASE PRESENTATION: A 49-year-old man of African descent presented to our hospital with a three-month history of weight loss, anorexia, abdominal distension, and general signs of cachexia and ascites on second presentation. At first presentation one year prior to this, he had undergone a laparotomy at our institution by a different team for intestinal obstruction secondary to adhesions with no biopsy taken. The patient's condition subsequently progressively deteriorated, and investigations including upper and lower gastrointestinal endoscopies and computed tomography of the abdomen were inconclusive, except for some free fluid in the peritoneal cavity and diffuse, mild thickening of the gut wall and mesentery. A second-look exploratory laparotomy revealed widespread nodular thickening of the visceral peritoneum with a striking, uniformly diffuse, erythematous, and velvety appearance. The peritoneal biopsy histology showed that the patient had malignant peritoneal mesothelioma. His condition deteriorated rapidly, and he died eight weeks after surgery. CONCLUSION: Our report aims to increase the diagnosing clinician's awareness of the cardinal features of malignant peritoneal mesothelioma and thus reduce diagnostic errors and delays in treatment.
format Online
Article
Text
id pubmed-3180415
institution National Center for Biotechnology Information
language English
publishDate 2011
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-31804152011-09-27 Malignant peritoneal mesothelioma presenting as recurrent adhesion obstruction in general surgery: a case report Naraynsingh, Vijay Ramdass, Michael J Lum, Crystal Lee J Med Case Reports Case Report INTRODUCTION: Malignant peritoneal mesothelioma is a well-described entity in many reports in the literature in which it has been associated with asbestosis. However, there is no information describing the gross appearance and cardinal features seen during laparotomy, hence it is easy for the unwary surgeon to miss the diagnosis of this rare condition. CASE PRESENTATION: A 49-year-old man of African descent presented to our hospital with a three-month history of weight loss, anorexia, abdominal distension, and general signs of cachexia and ascites on second presentation. At first presentation one year prior to this, he had undergone a laparotomy at our institution by a different team for intestinal obstruction secondary to adhesions with no biopsy taken. The patient's condition subsequently progressively deteriorated, and investigations including upper and lower gastrointestinal endoscopies and computed tomography of the abdomen were inconclusive, except for some free fluid in the peritoneal cavity and diffuse, mild thickening of the gut wall and mesentery. A second-look exploratory laparotomy revealed widespread nodular thickening of the visceral peritoneum with a striking, uniformly diffuse, erythematous, and velvety appearance. The peritoneal biopsy histology showed that the patient had malignant peritoneal mesothelioma. His condition deteriorated rapidly, and he died eight weeks after surgery. CONCLUSION: Our report aims to increase the diagnosing clinician's awareness of the cardinal features of malignant peritoneal mesothelioma and thus reduce diagnostic errors and delays in treatment. BioMed Central 2011-08-30 /pmc/articles/PMC3180415/ /pubmed/21878098 http://dx.doi.org/10.1186/1752-1947-5-420 Text en Copyright ©2011 Naraynsingh et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Naraynsingh, Vijay
Ramdass, Michael J
Lum, Crystal Lee
Malignant peritoneal mesothelioma presenting as recurrent adhesion obstruction in general surgery: a case report
title Malignant peritoneal mesothelioma presenting as recurrent adhesion obstruction in general surgery: a case report
title_full Malignant peritoneal mesothelioma presenting as recurrent adhesion obstruction in general surgery: a case report
title_fullStr Malignant peritoneal mesothelioma presenting as recurrent adhesion obstruction in general surgery: a case report
title_full_unstemmed Malignant peritoneal mesothelioma presenting as recurrent adhesion obstruction in general surgery: a case report
title_short Malignant peritoneal mesothelioma presenting as recurrent adhesion obstruction in general surgery: a case report
title_sort malignant peritoneal mesothelioma presenting as recurrent adhesion obstruction in general surgery: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3180415/
https://www.ncbi.nlm.nih.gov/pubmed/21878098
http://dx.doi.org/10.1186/1752-1947-5-420
work_keys_str_mv AT naraynsinghvijay malignantperitonealmesotheliomapresentingasrecurrentadhesionobstructioningeneralsurgeryacasereport
AT ramdassmichaelj malignantperitonealmesotheliomapresentingasrecurrentadhesionobstructioningeneralsurgeryacasereport
AT lumcrystallee malignantperitonealmesotheliomapresentingasrecurrentadhesionobstructioningeneralsurgeryacasereport