Nuclear-Targeted Deleted in Liver Cancer 1 (DLC1) Is Less Efficient in Exerting Its Tumor Suppressive Activity Both In Vitro and In Vivo

BACKGROUND: Deleted in liver cancer 1 (DLC1) serves as an important RhoGTPase activating protein (RhoGAP) protein that terminates active RhoA signaling in human cancers. Increasing evidence has demonstrated that the tumor suppressive activity of DLC1 depends not only on RhoGAP activity, but also rel...

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Detalles Bibliográficos
Autores principales: Chan, Lo-Kong, Ko, Frankie Chi Fat, Sze, Karen Man-Fong, Ng, Irene Oi-Lin, Yam, Judy Wai Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3180446/
https://www.ncbi.nlm.nih.gov/pubmed/21966542
http://dx.doi.org/10.1371/journal.pone.0025547

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3180446/
https://www.ncbi.nlm.nih.gov/pubmed/21966542
http://dx.doi.org/10.1371/journal.pone.0025547

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