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The Importance of the Stem Cell Marker Prominin-1/CD133 in the Uptake of Transferrin and in Iron Metabolism in Human Colon Cancer Caco-2 Cells

As the pentaspan stem cell marker CD133 was shown to bind cholesterol and to localize in plasma membrane protrusions, we investigated a possible function for CD133 in endocytosis. Using the CD133 siRNA knockdown strategy and non-differentiated human colon cancer Caco-2 cells that constitutively over...

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Detalles Bibliográficos
Autores principales: Bourseau-Guilmain, Erika, Griveau, Audrey, Benoit, Jean-Pierre, Garcion, Emmanuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3180456/
https://www.ncbi.nlm.nih.gov/pubmed/21966538
http://dx.doi.org/10.1371/journal.pone.0025515

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