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Basal LAT-diacylglycerol-RasGRP1 Signals in T Cells Maintain TCRα Gene Expression

In contrast to the well-characterized T cell receptor (TCR) signaling pathways that induce genes that drive T cell development or polarization of naïve CD4 T cells into the diverse T(H)1, T(H)2, T(H)17 and T(reg) lineages, it is unclear what signals maintain specific gene expression in mature restin...

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Detalles Bibliográficos
Autores principales:	Markegard, Evan, Trager, Evan, Yang, Chih-wen Ou, Zhang, Weiguo, Weiss, Arthur, Roose, Jeroen P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3180458/ https://www.ncbi.nlm.nih.gov/pubmed/21966541 http://dx.doi.org/10.1371/journal.pone.0025540

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