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Leukocyte- and Platelet-Derived Microvesicle Interactions following In Vitro and In Vivo Activation of Toll-Like Receptor 4 by Lipopolysaccharide
BACKGROUND: Pro-coagulant membrane microvesicles (MV) derived from platelets and leukocytes are shed into the circulation following receptor-mediated activation, cell-cell interaction, and apoptosis. Platelets are sentinel markers of toll-like receptor 4 (TLR4) activation. Experiments were designed...
Autores principales: | Xiong, Jing, Miller, Virginia M., Hunter, Larry W., Li, Yunman, Jayachandran, Muthuvel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3180459/ https://www.ncbi.nlm.nih.gov/pubmed/21966536 http://dx.doi.org/10.1371/journal.pone.0025504 |
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