Squamous Cell Carcinoma of the Hilar Bile Duct

We herein report a rare case of squamous cell carcinoma of the hilar bile duct. A 66-year-old Japanese male patient was admitted to our hospital because of appetite loss and jaundice. Abdominal computed tomography revealed an enhanced mass measuring 10 × 30 mm in the hilar bile duct region. After un...

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Autores principales: Yamana, Ippei, Kawamoto, Shunji, Nagao, Shuji, Yoshida, Takahisa, Yamashita, Yuichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2011
Materias:
Published: August 2011
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3180664/
https://www.ncbi.nlm.nih.gov/pubmed/21960950
http://dx.doi.org/10.1159/000331051
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author Yamana, Ippei
Kawamoto, Shunji
Nagao, Shuji
Yoshida, Takahisa
Yamashita, Yuichi
author_facet Yamana, Ippei
Kawamoto, Shunji
Nagao, Shuji
Yoshida, Takahisa
Yamashita, Yuichi
author_sort Yamana, Ippei
collection PubMed
description We herein report a rare case of squamous cell carcinoma of the hilar bile duct. A 66-year-old Japanese male patient was admitted to our hospital because of appetite loss and jaundice. Abdominal computed tomography revealed an enhanced mass measuring 10 × 30 mm in the hilar bile duct region. After undergoing biliary drainage, the patient underwent extended right hepatic lobectomy with regional lymph nodes dissection. The tumor had invaded the right portal vein. Therefore, we also performed resection and reconstruction of the portal vein. Histopathologically, the carcinoma cells exhibited a solid structure with differentiation to squamous cell carcinoma with keratinization and intercellular bridges. Immunohistochemical staining of the tumor cells revealed positive cytokeratin staining and negative CAM 5.2 staining. Based on these findings, a definitive diagnosis of well-differentiated squamous cell carcinoma of the hilar bile duct was made.
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spelling pubmed-31806642011-09-29 Squamous Cell Carcinoma of the Hilar Bile Duct Yamana, Ippei Kawamoto, Shunji Nagao, Shuji Yoshida, Takahisa Yamashita, Yuichi Case Rep Gastroenterol Published: August 2011 We herein report a rare case of squamous cell carcinoma of the hilar bile duct. A 66-year-old Japanese male patient was admitted to our hospital because of appetite loss and jaundice. Abdominal computed tomography revealed an enhanced mass measuring 10 × 30 mm in the hilar bile duct region. After undergoing biliary drainage, the patient underwent extended right hepatic lobectomy with regional lymph nodes dissection. The tumor had invaded the right portal vein. Therefore, we also performed resection and reconstruction of the portal vein. Histopathologically, the carcinoma cells exhibited a solid structure with differentiation to squamous cell carcinoma with keratinization and intercellular bridges. Immunohistochemical staining of the tumor cells revealed positive cytokeratin staining and negative CAM 5.2 staining. Based on these findings, a definitive diagnosis of well-differentiated squamous cell carcinoma of the hilar bile duct was made. S. Karger AG 2011-08-22 /pmc/articles/PMC3180664/ /pubmed/21960950 http://dx.doi.org/10.1159/000331051 Text en Copyright © 2011 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial-No-Derivative-Works License (http://creativecommons.org/licenses/by-nc-nd/3.0/). Users may download, print and share this work on the Internet for noncommercial purposes only, provided the original work is properly cited, and a link to the original work on http://www.karger.com and the terms of this license are included in any shared versions.
spellingShingle Published: August 2011
Yamana, Ippei
Kawamoto, Shunji
Nagao, Shuji
Yoshida, Takahisa
Yamashita, Yuichi
Squamous Cell Carcinoma of the Hilar Bile Duct
title Squamous Cell Carcinoma of the Hilar Bile Duct
title_full Squamous Cell Carcinoma of the Hilar Bile Duct
title_fullStr Squamous Cell Carcinoma of the Hilar Bile Duct
title_full_unstemmed Squamous Cell Carcinoma of the Hilar Bile Duct
title_short Squamous Cell Carcinoma of the Hilar Bile Duct
title_sort squamous cell carcinoma of the hilar bile duct
topic Published: August 2011
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3180664/
https://www.ncbi.nlm.nih.gov/pubmed/21960950
http://dx.doi.org/10.1159/000331051
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AT nagaoshuji squamouscellcarcinomaofthehilarbileduct
AT yoshidatakahisa squamouscellcarcinomaofthehilarbileduct
AT yamashitayuichi squamouscellcarcinomaofthehilarbileduct

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