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Absence of N addition facilitates B cell development, but impairs immune responses

The programmed, stepwise acquisition of immunocompetence that marks the development of the fetal immune response proceeds during a period when both T cell receptor and immunoglobulin (Ig) repertoires exhibit reduced junctional diversity due to physiologic terminal deoxynucleotidyl transferase (TdT)...

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Detalles Bibliográficos
Autores principales:	Schelonka, Robert L., Ivanov, Ivaylo I., Vale, Andre M., Dimmitt, Reed A., Khaled, Mahnaz, Schroeder, Harry W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer-Verlag 2011
Materias:	Original Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3181008/ https://www.ncbi.nlm.nih.gov/pubmed/21660592 http://dx.doi.org/10.1007/s00251-011-0543-7

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