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Doxorubicin-loaded PEG-PCL copolymer micelles enhance cytotoxicity and intracellular accumulation of doxorubicin in adriamycin-resistant tumor cells

BACKGROUND: Multidrug resistance remains a major obstacle to successful cancer chemotherapy. Some chemical multidrug resistance inhibitors, such as ciclosporin and verapamil, have been reported to reverse resistance in tumor cells. However, the accompanying side effects have limited their clinical a...

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Detalles Bibliográficos
Autores principales: Diao, Yuan-Yuan, Li, Hao-Ying, Fu, Ying-Hua, Han, Min, Hu, Yu-Lan, Jiang, Hong-Liang, Tsutsumi, Yasuo, Wei, Qi-Chun, Chen, Da-Wei, Gao, Jian-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3181056/
https://www.ncbi.nlm.nih.gov/pubmed/21976972
http://dx.doi.org/10.2147/IJN.S23099

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