Anti-DR5 monoclonal antibody-mediated DTIC-loaded nanoparticles combining chemotherapy and immunotherapy for malignant melanoma: target formulation development and in vitro anticancer activity

BACKGROUND: The increased incidence of malignant melanoma in recent decades, along with its high mortality rate and pronounced resistance to therapy pose an enormous challenge. Novel therapeutic strategies, such as immunotherapy and targeted therapy, are urgently needed for melanoma. In this study,...

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Detalles Bibliográficos
Autores principales: Ding, Baoyue, Wu, Xin, Fan, Wei, Wu, Zhaoyong, Gao, Jing, Zhang, Wei, Ma, Lulu, Xiang, Wang, Zhu, Quangang, Liu, Jiyong, Ding, Xueying, Gao, Shen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2011
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3181059/
https://www.ncbi.nlm.nih.gov/pubmed/21976975
http://dx.doi.org/10.2147/IJN.S24094

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