Mesenchymal Transition and Dissemination of Cancer Cells Is Driven by Myeloid-Derived Suppressor Cells Infiltrating the Primary Tumor

In order to metastasize, cancer cells need to acquire a motile phenotype. Previously, development of this phenotype was thought to rely on the acquisition of selected, random mutations and thus would occur late in cancer progression. However, recent studies show that cancer cells disseminate early,...

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Detalles Bibliográficos
Autores principales: Toh, Benjamin, Wang, Xiaojie, Keeble, Jo, Sim, Wen Jing, Khoo, Karen, Wong, Wing-Cheong, Kato, Masashi, Prevost-Blondel, Armelle, Thiery, Jean-Paul, Abastado, Jean-Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3181226/
https://www.ncbi.nlm.nih.gov/pubmed/21980263
http://dx.doi.org/10.1371/journal.pbio.1001162

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