Tumor Necrosis Factor α-Converting Enzyme Inhibition Reverses Hepatic Steatosis and Improves Insulin Sensitivity Markers and Surgical Outcome in Mice

BACKGROUND: Hepatic steatosis is an established risk factor for complications following major hepatic resection. Pharmacological options to reverse steatosis prior to surgery, however, are lacking. We hypothesized that treatment with the pharmacologic tumor necrosis factor-α converting enzyme (TACE)...

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Detalles Bibliográficos
Autores principales: de Meijer, Vincent E., Le, Hau D., Meisel, Jonathan A., Sharma, Anisha K., Popov, Yury, Puder, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3181348/
https://www.ncbi.nlm.nih.gov/pubmed/21980496
http://dx.doi.org/10.1371/journal.pone.0025587

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