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Na(+) Channel β Subunits: Overachievers of the Ion Channel Family

Voltage-gated Na(+) channels (VGSCs) in mammals contain a pore-forming α subunit and one or more β subunits. There are five mammalian β subunits in total: β1, β1B, β2, β3, and β4, encoded by four genes: SCN1B–SCN4B. With the exception of the SCN1B splice variant, β1B, the β subunits are type I topol...

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Detalles Bibliográficos
Autores principales: Brackenbury, William J., Isom, Lori L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3181431/
https://www.ncbi.nlm.nih.gov/pubmed/22007171
http://dx.doi.org/10.3389/fphar.2011.00053