The pore structure and gating mechanism of K2P channels

Two-pore domain (K2P) potassium channels are important regulators of cellular electrical excitability. However, the structure of these channels and their gating mechanism, in particular the role of the bundle-crossing gate, are not well understood. Here, we report that quaternary ammonium (QA) ions...

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Detalles Bibliográficos
Autores principales: Piechotta, Paula L, Rapedius, Markus, Stansfeld, Phillip J, Bollepalli, Murali K, Erhlich, Gunter, Andres-Enguix, Isabelle, Fritzenschaft, Hariolf, Decher, Niels, Sansom, Mark S P, Tucker, Stephen J, Baukrowitz, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3181484/
https://www.ncbi.nlm.nih.gov/pubmed/21822218
http://dx.doi.org/10.1038/emboj.2011.268

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3181484/
https://www.ncbi.nlm.nih.gov/pubmed/21822218
http://dx.doi.org/10.1038/emboj.2011.268

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