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Diagnostic classification of psychiatric disorders and familial-genetic research

The validity of diagnostic definitions in psychiatry is directly related to the extent to which their etiology can be specified. However, since detailed knowledge of causal or susceptibility factors is lacking for most psychiatric disorders with a known or suspected familial-genetic origin, the curr...

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Detalles Bibliográficos
Autor principal: Maier, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Les Laboratoires Servier 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3181578/
https://www.ncbi.nlm.nih.gov/pubmed/22033840
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author Maier, Wolfgang
author_facet Maier, Wolfgang
author_sort Maier, Wolfgang
collection PubMed
description The validity of diagnostic definitions in psychiatry is directly related to the extent to which their etiology can be specified. However, since detailed knowledge of causal or susceptibility factors is lacking for most psychiatric disorders with a known or suspected familial-genetic origin, the current widely accepted classification systems largely fail to achieve this ideal. To illustrate this problem, this paper looks at the difficulties posed by the criteria for schizophrenia as laid down in the International Classification of Diseases, 10th revision (ICD-10) and the Diagnostic and Statistical Manual of Mental Disorders, Third Edition, Revised (DSM-III-R), and highlights the discrepancies between the majority of diagnostic boundaries and the various phenotype aggregation patterns observed in family studies. Progress in our understanding of psychiatric disorders requires to be firmly based on the findings of epidemiological studies as well as on a clear appreciation of the limitations of classification tools.
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spelling pubmed-31815782011-10-27 Diagnostic classification of psychiatric disorders and familial-genetic research Maier, Wolfgang Dialogues Clin Neurosci Clinical Research The validity of diagnostic definitions in psychiatry is directly related to the extent to which their etiology can be specified. However, since detailed knowledge of causal or susceptibility factors is lacking for most psychiatric disorders with a known or suspected familial-genetic origin, the current widely accepted classification systems largely fail to achieve this ideal. To illustrate this problem, this paper looks at the difficulties posed by the criteria for schizophrenia as laid down in the International Classification of Diseases, 10th revision (ICD-10) and the Diagnostic and Statistical Manual of Mental Disorders, Third Edition, Revised (DSM-III-R), and highlights the discrepancies between the majority of diagnostic boundaries and the various phenotype aggregation patterns observed in family studies. Progress in our understanding of psychiatric disorders requires to be firmly based on the findings of epidemiological studies as well as on a clear appreciation of the limitations of classification tools. Les Laboratoires Servier 1999-12 /pmc/articles/PMC3181578/ /pubmed/22033840 Text en Copyright: © 1999 LLS http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc-nd/3.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Research
Maier, Wolfgang
Diagnostic classification of psychiatric disorders and familial-genetic research
title Diagnostic classification of psychiatric disorders and familial-genetic research
title_full Diagnostic classification of psychiatric disorders and familial-genetic research
title_fullStr Diagnostic classification of psychiatric disorders and familial-genetic research
title_full_unstemmed Diagnostic classification of psychiatric disorders and familial-genetic research
title_short Diagnostic classification of psychiatric disorders and familial-genetic research
title_sort diagnostic classification of psychiatric disorders and familial-genetic research
topic Clinical Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3181578/
https://www.ncbi.nlm.nih.gov/pubmed/22033840
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