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Fleshing out the amyloid cascade hypothesis: the molecular biology of Alzheimer's disease
Alzheimer's disease (AD) is a disorder of two pathologies- plaques and tangles. The former have as a key constituent amyloid protein and the latter the microtubule-associaied protein tau. Genetics has demonstrated that changes in either protein are sufficient to cause dementia. The amyloid casc...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Les Laboratoires Servier
2000
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3181594/ https://www.ncbi.nlm.nih.gov/pubmed/22033981 |