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Understanding structural brain changes in schizophrenia

Schizophrenia is a chronic progressive disorder that has at its origin structural brain changes in both white and gray matter. It is likely that these changes begin prior to the onset of clinical symptoms in cortical regions, particularly those concerned with language processing. Later, they can be...

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Detalles Bibliográficos
Autores principales: DeLisi, Lynn E., Szulc, Kamila U., Bertisch, Hilary C., Majcher, Magda, Brown, Kyle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Les Laboratoires Servier 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3181763/
https://www.ncbi.nlm.nih.gov/pubmed/16640116
Descripción
Sumario:Schizophrenia is a chronic progressive disorder that has at its origin structural brain changes in both white and gray matter. It is likely that these changes begin prior to the onset of clinical symptoms in cortical regions, particularly those concerned with language processing. Later, they can be detected by progressive ventricular enlargement. Current magnetic resonance imaging (MRI) technology can provide a valuable tool for detecting early changes in cortical atrophy and anomalous language processing, which may be predictive of who will develop schizophrenia.